Singh will visit the country from August 23 to 26 at the invitation of the US Secretary of Defence Mr Lloyd Austin.
"During the visit, the Raksha Mantri will hold a bilateral meeting with his US counterpart Secretary Austin. He will also meet the US Assistant to the President for National Security Affairs Mr Jake Sullivan," read a statement issued by the Indian government.
The visit comes in the backdrop of the growing momentum in India-US relations and defence engagements at multiple levels.
"The visit is expected to further deepen and broaden the India-US Comprehensive Global Strategic Partnership," the statement said.
Rajnath Singh will also chair a high-level roundtable meeting with the US defence industry on the ongoing and future defence collaborations.
He will also interact with the Indian community during the visit.