Iran launched another barrage of ballistic missiles towards the densely populated regions of Israel, prompting the sounding of sirens in the affected areas, media reports said.

Iran announced that it has responded to the Israeli onslaught across the Gulf nations, in which Tehran has faced the majority of the blows.

The Israel Defence Forces (IDF) has also confirmed the incoming missile attack in its Telegram channel.

"A short while ago, the IDF identified missiles launched from Iran towards the territory of the State of Israel. Defensive systems are operating to intercept the threat," it said.

"Upon receiving an alert, the public is instructed to enter a protected space and remain there until further notice. Leaving the protected space is only permitted following an explicit directive. Continue to follow the instructions of the Home Front Command," it added in its caution to its citizens.

Meanwhile, Israel's Prime Minister Benjamin Netanyahu has warned that killing Iran's Supreme Leader, Ayatollah Ali Khamenei, will end the conflict.

His remark comes a day after US President Donald Trump vetoed this plan.

"It's not going to escalate the conflict, it's going to end the conflict," Netanyahu told ABC News in an interview.

The Israel-Iran conflict has spiraled into the fourth day. Israel said the attack was necessary, claiming that Iran was on the verge of gaining the capability of making a nuclear weapon - a red line for Tel Aviv and Washington, DC.

Israeli forces have already attacked nuclear infrastructure in Tehran besides striking its oil depot.

The headquarters of the Iranian state television, Republic of Iran News Network (IRINN), operated by IRIB, was hit by an Israeli strike on Monday evening, which abruptly halted its live broadcast, media reports said.

According to the Iranian media, the explosion occurred while a presenter was delivering a live on-air criticism of Israel. Moments later, she was seen leaving the broadcast.

The Israel Defense Forces on Monday claimed it had eliminated four high-ranking Iranian intelligence officials during a precision airstrike carried out by Israeli fighter jets in Tehran.

The deceased included the chief of the Intelligence Organisation of the Islamic Revolutionary Guard Corps (IRGC).

"The IDF eliminated 4 senior Iranian intelligence officials, including the Head of the IRGC’s Intelligence Organization," the IDF wrote on X.

IDF said IAF fighter jets guided by precise intelligence struck a structure in Tehran housing top Iranian intelligence officials.

The deceased Iranian intelligence officials were identified as Mohammad Kazemi, Head of IRGC Intelligence Organization, Mohammad Hassan Mohaqiq, his deputy, Mohsen Bakri, Head of Quds Force Intelligence and Abu al-Fadl Nikouei, his deputy.